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ATP Citrate (pro-S)-Lyase MeSH Descriptor Data 2023


MeSH Heading
ATP Citrate (pro-S)-Lyase
Tree Number(s)
D08.811.913.050.331
Unique ID
D001275
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001275
Scope Note
An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
Entry Term(s)
ATP Citrate (pro-3S)-Lyase
ATP Citrate Lyase
ATP Citrate Synthase
ATP-Dependent Citrate Lyase
Citrate Cleavage Enzyme
Registry Number
EC 2.3.3.8
Related Numbers
9027-95-6
CAS Type 1 Name
ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating)
Previous Indexing
Lyases (1966-1972)
Public MeSH Note
98; see ATP CITRATE LYASE 1977-97; see KETOACID-LYASES 1973-76
History Note
98(73)
Date Established
1977/01/01
Date of Entry
1999/01/01
Revision Date
2005/06/30
ATP Citrate (pro-S)-Lyase Preferred
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