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Hydroxymethylglutaryl-CoA Synthase MeSH Descriptor Data 2024


MeSH Heading
Hydroxymethylglutaryl-CoA Synthase
Tree Number(s)
D08.811.913.050.612
Unique ID
D006904
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006904
Scope Note
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
Entry Version
HMG COA SYNTHASE
Entry Term(s)
3-hydroxy-3-methylglutaryl-coenzyme A synthase
HMG CoA Synthase
HMG-CoA synthase
Registry Number
EC 2.3.3.10
Related Numbers
9027-44-5
CAS Type 1 Name
(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)
Previous Indexing
Coenzyme A (1973-1974)
Glutarates (1973-1974)
Ketoacid-Lyases (1973-1974)
Public MeSH Note
1991; HMG-COA SYNTHASE was indexed under HYDROXYMETHYLGLUTARYL-COA SYNTHASE 2005-2008, & under COENZYME A LIGASES 2001-2005
History Note
1991(1975);
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2019/04/29
Hydroxymethylglutaryl-CoA Synthase Preferred
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