MeSH Browser

MeSH Heading: Serine C-Palmitoyltransferase
Tree Number(s): D08.811.913.050.668
Unique ID: D051102
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051102
Scope Note: A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
Entry Term(s): Long Chain Base Biosynthesis Protein 1; Long Chain Base Biosynthesis Protein 2; Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating); Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating); Serine Palmitoyltransferase; Serine Palmitoyltransferase 1; Serine Palmitoyltransferase 2; Serine Palmitoyltransferase, Long Chain Base Subunit 1; Serine Palmitoyltransferase, Long Chain Base Subunit 2; Serine-Palmitoyl-CoA Transferase 2
Registry Number: EC 2.3.1.50
Related Numbers: EC 2.3.1.50
Previous Indexing: Acyltransferases (1984-2005)
Public MeSH Note: 2006; SERINE C-PALMITOYLTRANSFERASE was indexed under ACYLTRANSFERASES 1984-2005
History Note: 2006(1984)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2005/08/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Serine C-Palmitoyltransferase MeSH Descriptor Data 2024