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CD3 Complex MeSH Descriptor Data 2025


MeSH Heading
CD3 Complex
Tree Number(s)
D23.050.301.264.894.095
D23.101.100.894.095
Unique ID
D017252
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017252
Scope Note
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
Entry Term(s)
Antigens, CD3
CD3 Antigen
CD3 Antigens
T3 Antigen
T3 Antigens
T3 Complex
Registry Numbers
0
Previous Indexing
Antigens (1983-1984)
Antigens, Differentiation, T-Lymphocyte (1988-1992)
Antigens, Surface (1983-1987)
Receptors, Antigen, T-Cell (1990-1992)
See Also
Receptors, Antigen, T-Cell
Public MeSH Note
2018; see ANTIGENS, CD3 1993-2017; CD3 COMPLEX was indexed under RECEPTORS, ANTIGEN, T-CELL 1990-92; under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92; under ANTIGENS, SURFACE 1983-87; and under ANTIGENS 1983-84; for T3 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92
History Note
2018 (1993); use T3 ANTIGEN COMPLEX 1983-92; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92
Date Established
1993/01/01
Date of Entry
1992/05/07
Revision Date
2017/06/02
CD3 Complex Preferred
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