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Insulin-Like Growth Factor I MeSH Descriptor Data 2025


MeSH Heading
Insulin-Like Growth Factor I
Tree Number(s)
D12.644.276.742.500.001
D12.776.124.862.001
D23.529.742.500.001
Unique ID
D007334
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007334
Scope Note
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Entry Term(s)
IGF-1
IGF-I
IGF-I-SmC
Insulin Like Growth Factor I
Insulin-Like Somatomedin Peptide I
Somatomedin C
Registry Numbers
67763-96-6
CAS Type 1 Name
Insulin-like growth factor I
NLM Classification #
QU 107
Previous Indexing
Growth Substances (1966-1985)
Insulin (1966-1985)
Peptides (1966-1985)
Somatomedins (1973-1985)
Sulfation Factor (1971-1972)
See Also
Receptor, IGF Type 1
Public MeSH Note
91; was see under SOMATOMEDINS 1986-90
History Note
91(86); was see under SOMATOMEDINS 1986-90
Date Established
1991/01/01
Date of Entry
2024/08/09
Revision Date
2024/06/11
Insulin-Like Growth Factor I Preferred
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