MeSH Browser

MeSH Heading: Pepsin A
Tree Number(s): D08.811.277.656.074.500.700; D08.811.277.656.300.048.700
Unique ID: D010434
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010434
Annotation: /biosyn /‌physiol permitted
Scope Note: Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
Entry Term(s): Pepsin; Pepsin 1; Pepsin 3
Pharm Action: Gastrointestinal Agents
Related Numbers: 9001-75-6
NLM Classification #: QV 66
Public MeSH Note: 91; was PEPSIN 1964-90
Online Note: use PEPSIN A to search PEPSIN 1966-90
History Note: 91; was PEPSIN 1964-90
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/07/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Pepsin A MeSH Descriptor Data 2024