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Receptor, Interferon alpha-beta MeSH Descriptor Data 2022


MeSH Heading
Receptor, Interferon alpha-beta
Tree Number(s)
D12.776.543.750.705.852.400.500
Unique ID
D053633
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053633
Scope Note
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
Entry Term(s)
IFN-alphaR
IFN-alphabetaR
IFNAR1 Subunit, Interferon alpha-beta Receptor
IFNAR2 Subunit, Interferon alpha-beta Receptor
IFNAR2.1 Subunit, Interferon alpha-beta Receptor
IFNAR2.2 Subunit, Interferon alpha-beta Receptor
Interferon alpha Receptor
Interferon alpha Receptors
Interferon alpha-beta Receptor
Interferon alpha-beta Receptor Chain 1
Interferon alpha-beta Receptor Chain 2
Interferon alpha-beta Receptor IFNAR1 Subunit
Interferon alpha-beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor-1
Interferon alpha-beta Receptor-2
Interferon alphabeta Receptors
Receptor, Interferon alpha
Type I Interferon Receptor
Registry Number
156986-95-7
Public MeSH Note
2007; INTERFERON ALPHA-BETA RECEPTOR was indexed under MEMBRANE PROTEINS and RECEPTORS, INTERFERON 1994-2006; INTERFERON ALPHA RECEPTOR was indexed under RECEPTORS, INTERFERON 1993-2006
History Note
2007(1993)
Date Established
2007/01/01
Date of Entry
2006/07/05
Receptor, Interferon alpha-beta Preferred
Interferon alpha-beta Receptor Chain 2 Narrower
Interferon alpha-beta Receptor Chain 1 Narrower
IFNAR2.1 Subunit, Interferon alpha-beta Receptor Narrower
IFNAR2.2 Subunit, Interferon alpha-beta Receptor Narrower
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