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Receptor, Interferon alpha-beta MeSH Descriptor Data 2025
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
Entry Term(s)
IFN-alphaR
IFN-alphabetaR
IFNAR1 Subunit, Interferon alpha-beta Receptor
IFNAR2 Subunit, Interferon alpha-beta Receptor
IFNAR2.1 Subunit, Interferon alpha-beta Receptor
IFNAR2.2 Subunit, Interferon alpha-beta Receptor
Interferon alpha Receptor
Interferon alpha Receptors
Interferon alpha-beta Receptor
Interferon alpha-beta Receptor Chain 1
Interferon alpha-beta Receptor Chain 2
Interferon alpha-beta Receptor IFNAR1 Subunit
Interferon alpha-beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor-1
Interferon alpha-beta Receptor-2
Interferon alphabeta Receptors
Receptor, Interferon alpha
Type I Interferon Receptor
Registry Numbers
156986-95-7
0
Public MeSH Note
2007; INTERFERON ALPHA-BETA RECEPTOR was indexed under MEMBRANE PROTEINS and RECEPTORS, INTERFERON 1994-2006; INTERFERON ALPHA RECEPTOR was indexed under RECEPTORS, INTERFERON 1993-2006
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.