MeSH Browser

MeSH Heading: Perilipin-1
Tree Number(s): D12.776.157.464.500.500
Unique ID: D000070778
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070778
Scope Note: A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
Entry Term(s): PERI Protein; Perilipin; Perilipin A Protein; Perilipin B Protein; Perilipin Protein; Plin Protein
Registry Numbers: 0
Public MeSH Note: 2017; PERILIPIN-1 was indexed under CARRIER PROTEINS and PHOSPHOPROTEINS 1991-2016.
History Note: 2017 (1991)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0188823
Registry Numbers: 0
Scope Note: A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
Terms: Perilipin-1 Preferred Term
Term UI T000890949
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2017); Perilipin A Protein
Term UI T000890950
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2017); Perilipin Protein
Term UI T000890948
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2017); Perilipin
Term UI T000893709
Date01/15/2016
LexicalTag NON
ThesaurusID NLM (2017); Perilipin B Protein
Term UI T000890953
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2017); PERI Protein
Term UI T000890986
Date11/24/2015
LexicalTag ABX
ThesaurusID NLM (2017); Plin Protein
Term UI T000890987
Date11/24/2015
LexicalTag ABX
ThesaurusID NLM (2017)

Perilipin-1 MeSH Descriptor Data 2025