MeSH Browser

MeSH Heading: Perilipin-3
Tree Number(s): D12.776.157.464.500.875
Unique ID: D000070796
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070796
Scope Note: A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
Entry Term(s): 47 kDa MPR-binding Protein; 47 kDa Mannose 6-Phosphate Receptor-Binding Protein; Cargo Selection Protein TIP47; Mannose-6-Phosphate Receptor-Binding Protein 1; PLIN3 Protein; Perilipin 3 Protein; Placental Protein 17; TIP47 Protein; Tail Interacting Protein of 47 kDa
Registry Number: 0
Public MeSH Note: 2017; PERILIPIN-3 was indexed under CARRIER PROTIENS 1983-2004; under DNA-BINDING PROTEINS, INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS, and PREGNANCY PROTEINS 1983-2011; and under VESICULAR TRANSPORT PROTEINS 2011-2016 1983-2011
History Note: 2017 (1983)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/19

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Lipid Droplet Associated Proteins [D12.776.157.464]
      - Perilipins [D12.776.157.464.500]
        
        Perilipin-1 [D12.776.157.464.500.500]
        
        Perilipin-2 [D12.776.157.464.500.750]
        
        Perilipin-3 [D12.776.157.464.500.875]
        
        Perilipin-4 [D12.776.157.464.500.906]
        
        Perilipin-5 [D12.776.157.464.500.937]

Perilipin-3 Preferred

Concept UI: M000612258
Registry Number: 0
Scope Note: A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
Terms: Perilipin-3 Preferred Term
Term UI T000891256
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017); TIP47 Protein
Term UI T000891258
Date11/30/2015
LexicalTag ACX
ThesaurusID NLM (2017); 47 kDa Mannose 6-Phosphate Receptor-Binding Protein
Term UI T000891259
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017); Tail Interacting Protein of 47 kDa
Term UI T000891265
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017); 47 kDa MPR-binding Protein
Term UI T000891261
Date11/30/2015
LexicalTag ABX
ThesaurusID NLM (2017); Cargo Selection Protein TIP47
Term UI T000891262
Date11/30/2015
LexicalTag ABX
ThesaurusID NLM (2017); Placental Protein 17
Term UI T000891263
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017); Mannose-6-Phosphate Receptor-Binding Protein 1
Term UI T000891264
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017); PLIN3 Protein
Term UI T000891257
Date11/30/2015
LexicalTag ABX
ThesaurusID NLM (2017); Perilipin 3 Protein
Term UI T000891260
Date11/30/2015
LexicalTag NON
ThesaurusID NLM (2017)

Perilipin-3 MeSH Descriptor Data 2024