MeSH Browser

MeSH Heading: Perilipin-2
Tree Number(s): D12.776.157.464.500.750
Unique ID: D000070780
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070780
Scope Note: A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
Entry Term(s): ADRP Protein; Adipophilin; Adipose Differentiation-Related Protein; PLIN2 Protein; Perilipin 2 Protein
Registry Numbers: 0
Public MeSH Note: 2017; PERILIPIN-2 was indexed under PEPTIDES 1998-2011; and under MEMBRANE PROTEINS 2011-2016
History Note: 2017 (1998)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/19

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0298231
Registry Numbers: 0
Scope Note: A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
Terms: Perilipin-2 Preferred Term
Term UI T000890989
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2011); Perilipin 2 Protein
Term UI T000890990
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2017); Adipophilin
Term UI T000890991
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (1998); Adipose Differentiation-Related Protein
Term UI T000890992
Date11/24/2015
LexicalTag NON
ThesaurusID NLM (2011); PLIN2 Protein
Term UI T000890993
Date11/24/2015
LexicalTag ABX
ThesaurusID NLM (2017); ADRP Protein
Term UI T000890994
Date11/24/2015
LexicalTag ABB
ThesaurusID NLM (2017)

Perilipin-2 MeSH Descriptor Data 2025