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Mismatch Repair Endonuclease PMS2 MeSH Descriptor Data 2022


MeSH Heading
Mismatch Repair Endonuclease PMS2
Tree Number(s)
D08.811.074.766.250
D08.811.277.040.025.215.250
D08.811.277.352.335.350.600
D12.776.260.540.250
Unique ID
D000070976
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070976
Scope Note
A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.
Entry Term(s)
PMS-2 Protein
PMS1 Homolog 2, Mismatch Repair Protein
PMS2 Protein
Postmeiotic Segregation Increased-S. cerevisiae-2
Registry Number
EC 3.6.1.3
Previous Indexing
Adenosine Triphosphatases (2001-2016)
DNA Repair Enzymes (2001-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/03/01
Mismatch Repair Endonuclease PMS2 Preferred
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