MeSH Browser

MeSH Heading: Poly (ADP-Ribose) Polymerase-1
Tree Number(s): D08.811.913.400.725.115.690.420
Unique ID: D000071137
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071137
Scope Note: A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.
Entry Term(s): NAD+ ADP-ribosyltransferase-1; PARP-1 Protein; PARP1 Protein; Poly (ADP-Ribose) Synthase-1
Registry Number: EC 2.4.2.30
Previous Indexing: ADP Ribose Transferases (2006-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/26

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000613201
Registry Number: EC 2.4.2.30
Scope Note: A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.
Terms: Poly (ADP-Ribose) Polymerase-1 Preferred Term
Term UI T000892919
Date12/30/2015
LexicalTag NON
ThesaurusID NLM (2017); Poly (ADP-Ribose) Synthase-1
Term UI T000892923
Date12/30/2015
LexicalTag NON
ThesaurusID NLM (2017); PARP1 Protein
Term UI T000892922
Date12/30/2015
LexicalTag ACX
ThesaurusID NLM (2017); PARP-1 Protein
Term UI T000892920
Date12/30/2015
LexicalTag ACX
ThesaurusID NLM (2017); NAD+ ADP-ribosyltransferase-1
Term UI T000892921
Date12/30/2015
LexicalTag ABX
ThesaurusID NLM (2017)

Poly (ADP-Ribose) Polymerase-1 MeSH Descriptor Data 2024