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Poly(ADP-ribose) Polymerases MeSH Descriptor Data 2022


MeSH Heading
Poly(ADP-ribose) Polymerases
Tree Number(s)
D08.811.913.400.725.115.690
Unique ID
D011065
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011065
Scope Note
Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
Entry Term(s)
ADP-Ribosyltransferase (Polymerizing)
PARP Polymerase
Poly ADP Ribose Polymerase
Poly ADP Ribose Transferase
Poly ADP-Ribose Synthase
Poly(ADP-Ribose) Synthase
Poly(ADP-Ribose) Transferase
Poly(ADP-ribose) Polymerase
Poly(ADPR) Polymerase
Poly(ADPribose) Polymerase
Registry Number
EC 2.4.2.30
Related Numbers
58319-92-9
CAS Type 1 Name
NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase
Previous Indexing
NAD Nucleosidase (1975-1976)
Nucleosidases (1966-1974)
See Also
Poly ADP Ribosylation
Public MeSH Note
2003; see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1977-1991, see NAD NUCLEOSIDASE 1975-1976
History Note
2003 (1977); use NAD NUCLEOSIDASE 1975-1976
Entry Combination
antagonists & inhibitors:Poly(ADP-ribose) Polymerase Inhibitors
Date Established
1986/01/01
Date of Entry
1976/04/19
Revision Date
2019/07/01
Poly(ADP-ribose) Polymerases Preferred
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