MeSH Browser

MeSH Heading: Forkhead Box Protein O3
Tree Number(s): D12.776.260.950.249.125; D12.776.930.977.249.125
Unique ID: D000071316
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071316
Scope Note: A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.
Entry Term(s): FOXO3 Protein; Forkhead in Rhabdomyosarcoma-Like 1 Protein
Previous Indexing: Forkhead Transcription Factors (2006-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000614016
Scope Note: A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.
Terms: Forkhead Box Protein O3 Preferred Term
Term UI T000897310
Date03/18/2016
LexicalTag NON
ThesaurusID NLM (2017); Forkhead in Rhabdomyosarcoma-Like 1 Protein
Term UI T000894402
Date01/29/2016
LexicalTag NON
ThesaurusID NLM (2017); FOXO3 Protein
Term UI T000894403
Date01/29/2016
LexicalTag ABX
ThesaurusID NLM (2017)

Forkhead Box Protein O3 MeSH Descriptor Data 2024