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Forkhead Box Protein O3 MeSH Descriptor Data 2022


MeSH Heading
Forkhead Box Protein O3
Tree Number(s)
D12.776.260.950.249.125
D12.776.930.977.249.125
Unique ID
D000071316
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071316
Scope Note
A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.
Entry Term(s)
FOXO3 Protein
Forkhead in Rhabdomyosarcoma-Like 1 Protein
Registry Number
0
Previous Indexing
Forkhead Transcription Factors (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/04/15
Forkhead Box Protein O3 Preferred
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