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Forkhead Box Protein L2 MeSH Descriptor Data 2022


MeSH Heading
Forkhead Box Protein L2
Tree Number(s)
D12.776.260.950.249.032
D12.776.930.977.249.032
Unique ID
D000074842
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074842
Scope Note
A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).
Entry Term(s)
FOXL2 Protein
Forkhead Box L2 Protein
Registry Number
0
Previous Indexing
Forkhead Transcription Factors (2006-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/05/22
Forkhead Box Protein L2 Preferred
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