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Transcription Factor HES-1 MeSH Descriptor Data 2022


MeSH Heading
Transcription Factor HES-1
Tree Number(s)
D12.776.260.103.844
D12.776.930.125.844
Unique ID
D000072056
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072056
Scope Note
A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.
Entry Term(s)
Hairy and Enhancer of Split 1 Protein
Hairy-Like Transcription Factor
Registry Number
0
Previous Indexing
Basic Helix-Loop-Helix Transcription Factors (1994-2016)
Homeodomain Proteins (1994-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/27
Transcription Factor HES-1 Preferred
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