MeSH Browser

MeSH Heading: TRPA1 Cation Channel
Tree Number(s): D12.776.157.530.400.901.250; D12.776.543.585.400.901.250
Unique ID: D000074025
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074025
Scope Note: A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
Entry Term(s): TRPA1 Channel; Transient Receptor Potential Cation Channel Subfamily A, Member 1
Registry Numbers: 0
Previous Indexing: Calcium Channels (2003-2017); Nerve Tissue Proteins (2003-2017); Transient Receptor Potential Channels (2006-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000625224
Registry Numbers: 0
Scope Note: A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
Terms: TRPA1 Cation Channel Preferred Term
Term UI T000913639
Date01/05/2017
LexicalTag ABX
ThesaurusID NLM (2018); Transient Receptor Potential Cation Channel Subfamily A, Member 1
Term UI T000913640
Date01/05/2017
LexicalTag NON
ThesaurusID NLM (2018); TRPA1 Channel
Term UI T000913641
Date01/05/2017
LexicalTag ABX
ThesaurusID NLM (2018)

TRPA1 Cation Channel MeSH Descriptor Data 2024