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Transient Receptor Potential Channels MeSH Descriptor Data 2022


MeSH Heading
Transient Receptor Potential Channels
Tree Number(s)
D12.776.157.530.400.901
D12.776.543.585.400.901
Unique ID
D050051
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050051
Annotation
note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN
Scope Note
A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
Entry Version
TRANSIENT RECEPT POTENTIAL CHANNELS
Entry Term(s)
TRP Cation Channel
TRP Cation Channels
TRP Membrane Proteins
Transient Receptor Potential Cation Channel
Transient Receptor Potential Cation Channels
Transient Receptor Potential Channel
Registry Number
0
Previous Indexing
Calcium Channels (1989-2005)
Ion Channels (1995-2005)
Public MeSH Note
2006
History Note
2006
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2020/05/27
Transient Receptor Potential Channels Preferred
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