MeSH Browser

MeSH Heading: Sodium-Hydrogen Exchanger 1
Tree Number(s): D12.776.157.530.450.162.775.500; D12.776.157.530.937.703.500; D12.776.543.550.190.775.500; D12.776.543.585.450.162.775.500; D12.776.543.585.937.828.500
Unique ID: D000074082
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074082
Scope Note: A sodium-hydrogen antiporter expressed by many cell types, especially on the basolateral surfaces of EPITHELIAL CELLS. It functions through an inward sodium ion chemical gradient to eliminate acids (protons) generated by metabolism and regulate intracellular pH. It is highly sensitive to AMILORIDE.
Entry Term(s): Na(+)-H(+) Exchanger 1; SLC9A1 Protein; Solute Carrier Family 9 Member 1
Registry Numbers: 0
Previous Indexing: Cation Transport Proteins (2004-2017); Sodium-Hydrogen Exchangers (2004-2017)
Public MeSH Note: 2018
History Note: 2018
Date Introduced: 2018/01/01
Last Updated: 2018/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000625447
Registry Numbers: 0
Scope Note: A sodium-hydrogen antiporter expressed by many cell types, especially on the basolateral surfaces of EPITHELIAL CELLS. It functions through an inward sodium ion chemical gradient to eliminate acids (protons) generated by metabolism and regulate intracellular pH. It is highly sensitive to AMILORIDE.
Terms: Sodium-Hydrogen Exchanger 1 Preferred Term
Term UI T000913993
Date01/11/2017
LexicalTag NON
ThesaurusID NLM (2018); Solute Carrier Family 9 Member 1
Term UI T000913997
Date01/11/2017
LexicalTag NON
ThesaurusID NLM (2018); Na(+)-H(+) Exchanger 1
Term UI T000913994
Date01/11/2017
LexicalTag ABX
ThesaurusID NLM (2018); SLC9A1 Protein
Term UI T000913996
Date01/11/2017
LexicalTag ABX
ThesaurusID NLM (2018)

Sodium-Hydrogen Exchanger 1 MeSH Descriptor Data 2026