MeSH Browser

MeSH Heading: Terbinafine
Tree Number(s): D02.455.426.559.847.638.953; D04.615.638.953
Unique ID: D000077291
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077291
Scope Note: A naphthalene derivative that inhibits fungal SQUALENE EPOXIDASE and is used to treat DERMATOMYCOSES of the skin and nails.
Entry Term(s): (E)-N-(6,6-Dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride; DA 5505; Lamisil; SF 86-327; SF-86-327; TDT-067; Terbinafine Hydrochloride; Terbinafine, (Z)-; Terbinafine, (Z)-isomer
Pharm Action: Antifungal Agents
Enzyme Inhibitors
Related Numbers: 012C11ZU6G; 78628-81-6; 91161-71-6; S76S370M70
CAS Type 1 Name: 1-Naphthalenemethanamine, N-((2E)-6,6-dimethyl-2-hepten-4-yn-1-yl)-N-methyl-
Public MeSH Note: 2019; TERBINAFINE was indexed under NAPHTHALENES 1984-2018
History Note: 2019 (1984)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Polycyclic Aromatic Hydrocarbons [D02.455.426.559.847]
        
        Naphthalenes [D02.455.426.559.847.638]
        
        Acenaphthenes [D02.455.426.559.847.638.059]
        
        Adapalene [D02.455.426.559.847.638.090]
        
        Bunaftine [D02.455.426.559.847.638.120]
        
        Carbaryl [D02.455.426.559.847.638.162]
        
        Cinacalcet [D02.455.426.559.847.638.183]
        
        Dansyl Compounds [D02.455.426.559.847.638.204]
        
        Lovastatin [D02.455.426.559.847.638.400]
        
        Naphthaleneacetic Acids [D02.455.426.559.847.638.472]
        
        Naphthalenesulfonates [D02.455.426.559.847.638.555]
        
        Naphthols [D02.455.426.559.847.638.638]
        
        Naphthoquinones [D02.455.426.559.847.638.721]
        
        1-Naphthylamine [D02.455.426.559.847.638.845]
        
        2-Naphthylamine [D02.455.426.559.847.638.850]
        
        1-Naphthylisothiocyanate [D02.455.426.559.847.638.870]
        
        Naphthylvinylpyridine [D02.455.426.559.847.638.900]
        
        Pravastatin [D02.455.426.559.847.638.930]
        
        Propranolol [D02.455.426.559.847.638.945]
        
        Terbinafine [D02.455.426.559.847.638.953]
        
        Tetrahydronaphthalenes [D02.455.426.559.847.638.960]
        
        Tolnaftate [D02.455.426.559.847.638.975]

Polycyclic Compounds [D04]
- Polycyclic Aromatic Hydrocarbons [D04.615]
  - Naphthalenes [D04.615.638]

Terbinafine Preferred

SF 86-327 Narrower

Terbinafine, (Z)-isomer Narrower

Terbinafine Hydrochloride Narrower

Lamisil Narrower

TDT-067 Narrower

DA 5505 Narrower

(E)-N-(6,6-Dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride Narrower

Terbinafine MeSH Descriptor Data 2024