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Squalene Monooxygenase MeSH Descriptor Data 2023


MeSH Heading
Squalene Monooxygenase
Tree Number(s)
D08.811.682.690.708.749
Unique ID
D050603
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050603
Scope Note
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
Entry Term(s)
Squalene Epoxidase
Squalene Monooxygenase (2,3-Epoxidizing)
Registry Number
EC 1.14.14.17
Related Numbers
9029-62-3
Public MeSH Note
2006; SQUALENE MONOOXYGENASE was indexed under OXYGENASES 1981-2005 & ETHERS, CYCLIC 1970-1980
History Note
2006(1980); use ETHERS, CYCLIC 1970-1979
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/06/01
Squalene Monooxygenase Preferred
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