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Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase MeSH Descriptor Data 2022


MeSH Heading
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
Tree Number(s)
D08.811.682.690.708.660
Unique ID
D008240
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008240
Scope Note
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.
Entry Term(s)
Collagen Lysyl Hydroxylase
Lysine 2-Oxoglutarate Dioxygenase
Lysine Hydroxylase
Lysyl Hydroxylase
Protocollagen Lysyl Hydroxylase
Registry Number
EC 1.14.11.4
CAS Type 1 Name
Procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)
Previous Indexing
Hydroxylases (1966-1976)
Ketoglutaric Acids (1966-1976)
Lysine (1966-1976)
Public MeSH Note
92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90)
Online Note
use PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE to search LYSINE HYDROXYLASE 1977-91
History Note
92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90)
Date Established
1991/01/01
Date of Entry
1976/04/27
Revision Date
2004/07/07
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase Preferred
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