CD68 Molecule MeSH Descriptor Data 2024

MeSH Heading: CD68 Molecule
Tree Number(s): D09.400.430.890.550.125; D12.776.395.550.550.125; D12.776.543.550.527.125; D12.776.543.750.705.940.718.500; D12.776.543.750.710.450.750.718.500; D23.050.301.264.035.567; D23.050.301.264.900.023; D23.101.100.110.567; D23.101.100.900.023
Unique ID: D000097382
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097382
Scope Note: A single-pass type 1 transmembrane glycoprotein that localizes to LYSOSOMES; ENDOSOMES; and cell surface CELL MEMBRANES. It is a member of the lysosomal associated membrane glycoprotein family and the scavenger receptor family. The highly glycosylated extracellular domain binds to tissue- and organ-specific LECTINS or SELECTINS.
Entry Term(s): CD68 Antigen; LAMP4 Protein; Lysosomal-Associated Membrane Protein 4; Macrosialin; SCARD1 Protein; Scavenger Receptor Class D, Member 1
Registry Number: 0
Public MeSH Note: 2024; was indexed as ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC and ANTIGENS, CD 1991-2023
History Note: 2024 (1991)
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/26

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Lysosomal Membrane Proteins [D09.400.430.890.550]
        
        CD68 Molecule [D09.400.430.890.550.125]
        
        Tetraspanin 30 [D09.400.430.890.550.249]
        
        Lysosomal-Associated Membrane Protein 1 [D09.400.430.890.550.500]
        
        Lysosomal-Associated Membrane Protein 2 [D09.400.430.890.550.750]
        
        Lysosomal-Associated Membrane Protein 3 [D09.400.430.890.550.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Lysosomal Membrane Proteins [D12.776.395.550.550]
        
        CD68 Molecule [D12.776.395.550.550.125]
        
        Tetraspanin 30 [D12.776.395.550.550.249]
        
        Lysosomal-Associated Membrane Protein 1 [D12.776.395.550.550.500]
        
        Lysosomal-Associated Membrane Protein 2 [D12.776.395.550.550.750]
        
        Lysosomal-Associated Membrane Protein 3 [D12.776.395.550.550.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Lysosomal Membrane Proteins [D12.776.543.550.527]
        
        CD68 Molecule [D12.776.543.550.527.125]
        
        Tetraspanin 30 [D12.776.543.550.527.249]
        
        Lysosomal-Associated Membrane Protein 1 [D12.776.543.550.527.500]
        
        Lysosomal-Associated Membrane Protein 2 [D12.776.543.550.527.750]
        
        Lysosomal-Associated Membrane Protein 3 [D12.776.543.550.527.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Scavenger [D12.776.543.750.705.940]
        
        Scavenger Receptors, Class D [D12.776.543.750.705.940.718]
        
        CD68 Molecule [D12.776.543.750.705.940.718.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Lipoprotein [D12.776.543.750.710]
        
        Receptors, LDL [D12.776.543.750.710.450]
        
        Receptors, Scavenger [D12.776.543.750.710.450.750]
        
        Scavenger Receptors, Class D [D12.776.543.750.710.450.750.718]
        
        CD68 Molecule [D12.776.543.750.710.450.750.718.500]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Antigens, Differentiation [D23.050.301.264]
      - Antigens, CD [D23.050.301.264.035]
        
        Antigens, CD1 [D23.050.301.264.035.100]
        
        Antigens, CD7 [D23.050.301.264.035.107]
        
        Antigens, CD19 [D23.050.301.264.035.119]
        
        Antigens, CD20 [D23.050.301.264.035.120]
        
        Antigens, CD34 [D23.050.301.264.035.134]
        
        CD68 Molecule [D23.050.301.264.035.567]
        
        CD83 Antigen [D23.050.301.264.035.783]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Antigens, Differentiation [D23.050.301.264]
      - Antigens, Differentiation, Myelomonocytic [D23.050.301.264.900]
        
        CD68 Molecule [D23.050.301.264.900.023]
        
        Lipopolysaccharide Receptors [D23.050.301.264.900.045]
        
        Lewis X Antigen [D23.050.301.264.900.050]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D23.050.301.264.900.131]
        
        Sialic Acid Binding Ig-like Lectin 3 [D23.050.301.264.900.565]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]
    - Antigens, CD [D23.101.100.110]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]
    - Antigens, Differentiation, Myelomonocytic [D23.101.100.900]

CD68 Molecule Preferred

Concept UI: M000763930
Registry Number: 0
Scope Note: A single-pass type 1 transmembrane glycoprotein that localizes to LYSOSOMES; ENDOSOMES; and cell surface CELL MEMBRANES. It is a member of the lysosomal associated membrane glycoprotein family and the scavenger receptor family. The highly glycosylated extracellular domain binds to tissue- and organ-specific LECTINS or SELECTINS.
Terms: CD68 Molecule Preferred Term
Term UI T001135576
Date03/24/2023
LexicalTag ABX
ThesaurusID NLM (2024); Scavenger Receptor Class D, Member 1
Term UI T001135580
Date03/24/2023
LexicalTag NON
ThesaurusID NLM (2024); Macrosialin
Term UI T001137221
Date05/05/2023
LexicalTag NON
ThesaurusID NLM (2024); Lysosomal-Associated Membrane Protein 4
Term UI T001135578
Date03/24/2023
LexicalTag NON
ThesaurusID NLM (2024); SCARD1 Protein
Term UI T001135585
Date03/27/2023
LexicalTag ABX
ThesaurusID NLM (2024); LAMP4 Protein
Term UI T001135579
Date03/24/2023
LexicalTag NON
ThesaurusID NLM (2024); CD68 Antigen
Term UI T001135577
Date03/24/2023
LexicalTag ABX
ThesaurusID NLM (2024)

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