NLM Logo

Chlormethiazole MeSH Descriptor Data 2024


MeSH Heading
Chlormethiazole
Tree Number(s)
D02.886.675.180
D03.383.129.708.180
Unique ID
D002719
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002719
Scope Note
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
Entry Term(s)
Clomethiazole
Distraneurin
Pharm Action
Anticonvulsants
Hypnotics and Sedatives
Neuroprotective Agents
GABA Modulators
Related Numbers
533-45-9
CAS Type 1 Name
Thiazole, 5-(2-chloroethyl)-4-methyl-
Previous Indexing
Hypnotics and Sedatives (1966-1967)
Thiazoles (1966-1967)
Public MeSH Note
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
History Note
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
Date Established
1968/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/28
Chlormethiazole Preferred
Distraneurin Narrower
page delivered in 0.14s