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Microbial Collagenase MeSH Descriptor Data 2024


MeSH Heading
Microbial Collagenase
Tree Number(s)
D08.811.277.656.300.480.205.500
D08.811.277.656.675.374.205.500
Unique ID
D003012
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003012
Scope Note
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Entry Term(s)
Clostridiopeptidase A
Clostridium histolyticum Collagenase
Collagenase Clostridium histolyticum
Collagenase, Microbial
Collagenase-Like Peptidase
Collalysine
Nucleolysin
Registry Number
EC 3.4.24.3
NLM Classification #
QU 136
Public MeSH Note
94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90
Online Note
use MICROBIAL COLLAGENASE to search CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93 & CLOSTRIDIOPEPTIDASE A 1966-90
History Note
94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2014/06/12
Microbial Collagenase Preferred
Collagenase-Like Peptidase Broader
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