Matrix Metalloproteinase 1 MeSH Descriptor Data 2024

MeSH Heading: Matrix Metalloproteinase 1
Tree Number(s): D08.811.277.656.300.480.205.351; D08.811.277.656.300.480.525.700.100; D08.811.277.656.675.374.205.351; D08.811.277.656.675.374.525.700.100; D12.776.467.836.100
Unique ID: D020781
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020781
Scope Note: A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.
Entry Term(s): Interstitial Collagenase; MMP-1 Metalloproteinase; MMP1 Metalloproteinase; Matrix Metalloproteinase-1; Pro-Matrix Metalloproteinase-1; Promatrixmetalloproteinase-1; proMMP-1
Previous Indexing: Collagenases (1991-1999)
Public MeSH Note: 2007; see INTERSTITIAL COLLAGENASE 2000-2006; PRO-MATRIX METALLOPROTEINASE 1 was indexed under ENZYME PRECURSORS & COLLAGENASES 1995-2006
History Note: 2007(2000)
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2021/05/21

Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Collagenases [D08.811.277.656.300.480.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.205.363]
        
        Microbial Collagenase [D08.811.277.656.300.480.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Matrix Metalloproteinases [D08.811.277.656.300.480.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
        
        Bone Morphogenetic Protein 1 [D08.811.277.656.300.480.525.700.049]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.300.480.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.300.480.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.300.480.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.300.480.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.300.480.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.300.480.525.700.800]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Collagenases [D08.811.277.656.675.374.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.205.363]
        
        Microbial Collagenase [D08.811.277.656.675.374.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Matrix Metalloproteinases [D08.811.277.656.675.374.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.675.374.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.675.374.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.675.374.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.675.374.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.675.374.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.675.374.525.700.800]
        
        Tolloid-Like Metalloproteinases [D08.811.277.656.675.374.525.700.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Matrix Metalloproteinases, Secreted [D12.776.467.836]

Matrix Metalloproteinase 1 Preferred

Concept UI: M0188742
Scope Note: A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.
Terms: Matrix Metalloproteinase 1 Preferred Term
Term UI T664558
Date01/18/2006
LexicalTag NON
ThesaurusID NLM (2007); Matrix Metalloproteinase-1
Term UI T218744
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Interstitial Collagenase
Term UI T218747
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); MMP-1 Metalloproteinase
Term UI T664566
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); MMP1 Metalloproteinase
Term UI T664580
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007)

Pro-Matrix Metalloproteinase-1 Narrower

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