MeSH Browser

MeSH Heading: Matrix Metalloproteinase 12
Tree Number(s): D08.811.277.656.300.480.525.700.500; D08.811.277.656.675.374.525.700.500; D12.776.467.836.500
Unique ID: D053508
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053508
Scope Note: A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
Entry Term(s): MMP-12 Metalloproteinase; MMP12 Metalloproteinase; Macrophage Metalloelastase; Macrophage-Specific Metalloelastase; Metalloproteinase Elastase
Public MeSH Note: 2007; MATRIX METALLOPROTEINASE 12 was indexed under METALLOENDOPETIDASES 1987-2006
History Note: 2007(1987)
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2021/05/21

Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0149080
Scope Note: A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
Terms: Matrix Metalloproteinase 12 Preferred Term
Term UI T457016
Date08/11/2001
LexicalTag NON
ThesaurusID NLM (2007); Macrophage Metalloelastase
Term UI T179085
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Macrophage-Specific Metalloelastase
Term UI T179086
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Metalloproteinase Elastase
Term UI T179087
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); MMP-12 Metalloproteinase
Term UI T664591
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); MMP12 Metalloproteinase
Term UI T664592
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007)

Matrix Metalloproteinase 12 MeSH Descriptor Data 2024