Matrix Metalloproteinase 8 MeSH Descriptor Data 2024

MeSH Heading: Matrix Metalloproteinase 8
Tree Number(s): D08.811.277.656.300.480.205.358; D08.811.277.656.300.480.525.700.300; D08.811.277.656.675.374.205.358; D08.811.277.656.675.374.525.700.300; D12.776.467.836.300
Unique ID: D020784
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020784
Scope Note: A member of the MATRIX METALLOPROTEINASES that cleaves triple-helical COLLAGEN types I, II, and III.
Entry Term(s): Collagenase-2; Fibroblast Collagenase; MMP-8 Metalloproteinase; MMP8 Metalloproteinase; Matrix Metalloproteinase-8; Neutrophil Collagenase
Registry Number: EC 3.4.24.34
Previous Indexing: Collagenases (1992-1999)
Public MeSH Note: 2000; see NEUTROPHIL COLLAGENASE 2000-2006; MATRIX METALLOPROTEINASE 8 was indexed under COLLAGENASES 1992-1999
History Note: 2007(2000)
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2021/05/21

Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Collagenases [D08.811.277.656.300.480.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.205.363]
        
        Microbial Collagenase [D08.811.277.656.300.480.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Matrix Metalloproteinases [D08.811.277.656.300.480.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
        
        Bone Morphogenetic Protein 1 [D08.811.277.656.300.480.525.700.049]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.300.480.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.300.480.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.300.480.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.300.480.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.300.480.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.300.480.525.700.800]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Collagenases [D08.811.277.656.675.374.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.205.363]
        
        Microbial Collagenase [D08.811.277.656.675.374.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Matrix Metalloproteinases [D08.811.277.656.675.374.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.675.374.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.675.374.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.675.374.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.675.374.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.675.374.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.675.374.525.700.800]
        
        Tolloid-Like Metalloproteinases [D08.811.277.656.675.374.525.700.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Matrix Metalloproteinases, Secreted [D12.776.467.836]

Matrix Metalloproteinase 8 Preferred

Concept UI: M0206959
Registry Number: EC 3.4.24.34
Scope Note: A member of the MATRIX METALLOPROTEINASES that cleaves triple-helical COLLAGEN types I, II, and III.
Terms: Matrix Metalloproteinase 8 Preferred Term
Term UI T664561
Date01/18/2006
LexicalTag NON
ThesaurusID NLM (2007); Matrix Metalloproteinase-8
Term UI T236963
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Neutrophil Collagenase
Term UI T236964
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); MMP8 Metalloproteinase
Term UI T664584
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); MMP-8 Metalloproteinase
Term UI T664570
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); Fibroblast Collagenase
Term UI T236962
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Collagenase-2
Term UI T664491
Date01/18/2006
LexicalTag NON
ThesaurusID NLM (2007)

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