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Encephalomyelitis, Autoimmune, Experimental MeSH Descriptor Data 2022


MeSH Heading
Encephalomyelitis, Autoimmune, Experimental
Tree Number(s)
C10.114.703.300
C10.228.140.695.562.250
C10.314.350.250
C20.111.258.625.300
E05.598.500.500.500
Unique ID
D004681
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004681
Annotation
coordinate with specific demyelinating disease if pertinent
Scope Note
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Entry Version
ENCEPH AUTOIMMUNE EXPER
Entry Term(s)
Allergic Encephalomyelitis
Allergic Encephalomyelitis, Experimental
Autoimmune Encephalomyelitis, Experimental
Autoimmune Experimental Encephalomyelitis
Encephalomyelitis, Allergic
Encephalomyelitis, Experimental Autoimmune
Experimental Allergic Encephalomyelitis
Experimental Autoimmune Encephalomyelitis
NLM Classification #
WL 351
Public MeSH Note
2005; see ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE 2000-2004, see ENCEPHALOMYELITIS, ALLERGIC 1964-1999
History Note
2005 (1964)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Encephalomyelitis, Autoimmune, Experimental Preferred
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