MeSH Browser

MeSH Heading: Encephalomyelitis, Autoimmune, Experimental
Tree Number(s): C10.114.703.300; C10.228.140.695.562.250; C10.314.350.250; C20.111.258.625.300; E05.598.500.500.500
Unique ID: D004681
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004681
Annotation: coordinate with specific demyelinating disease if pertinent
Scope Note: An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Entry Version: ENCEPH AUTOIMMUNE EXPER
Entry Term(s): Allergic Encephalomyelitis; Allergic Encephalomyelitis, Experimental; Autoimmune Encephalomyelitis, Experimental; Autoimmune Experimental Encephalomyelitis; Encephalomyelitis, Allergic; Encephalomyelitis, Experimental Autoimmune; Experimental Allergic Encephalomyelitis; Experimental Autoimmune Encephalomyelitis
NLM Classification #: WL 351
Public MeSH Note: 2005; see ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE 2000-2004, see ENCEPHALOMYELITIS, ALLERGIC 1964-1999
History Note: 2005 (1964)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2022/04/13

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
  - Nervous System Autoimmune Disease, Experimental [C10.114.703]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Leukoencephalopathies [C10.228.140.695]
      - Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
        
        Diffuse Cerebral Sclerosis of Schilder [C10.228.140.695.562.112]
        
        Encephalomyelitis, Acute Disseminated [C10.228.140.695.562.225]
        
        Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]

Nervous System Diseases [C10]
- Demyelinating Diseases [C10.314]
  - Demyelinating Autoimmune Diseases, CNS [C10.314.350]

Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
  - Autoimmune Diseases of the Nervous System [C20.111.258]
    - Nervous System Autoimmune Disease, Experimental [C20.111.258.625]

Investigative Techniques [E05]
- Models, Animal [E05.598]
  - Disease Models, Animal [E05.598.500]
    - Nervous System Autoimmune Disease, Experimental [E05.598.500.500]

Encephalomyelitis, Autoimmune, Experimental Preferred

Concept UI: M0007370
Scope Note: An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Terms: Encephalomyelitis, Autoimmune, Experimental Preferred Term
Term UI T014344
Date09/02/1994
LexicalTag NON
ThesaurusID NLM (1996); Allergic Encephalomyelitis, Experimental
Term UI T014340
Date11/28/1990
LexicalTag NON
ThesaurusID; Autoimmune Encephalomyelitis, Experimental
Term UI T014345
Date11/01/1994
LexicalTag NON
ThesaurusID NLM (1996); Autoimmune Experimental Encephalomyelitis
Term UI T365221
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Encephalomyelitis, Experimental Autoimmune
Term UI T014347
Date09/02/1994
LexicalTag NON
ThesaurusID NLM (1996); Experimental Allergic Encephalomyelitis
Term UI T014341
Date11/28/1990
LexicalTag NON
ThesaurusID NLM (1992); Experimental Autoimmune Encephalomyelitis
Term UI T014346
Date11/01/1994
LexicalTag NON
ThesaurusID NLM (1996)

Encephalomyelitis, Allergic Related

Encephalomyelitis, Autoimmune, Experimental MeSH Descriptor Data 2024