- Concept UI
- M0328219
- Scope Note
- Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
- Terms
-
Myasthenia Gravis, Autoimmune, Experimental
Preferred Term
Term UI
T573994
Date02/24/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
-
Myasthenia Gravis, Experimental Autoimmune
Term UI
T358219
Date10/12/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Myasthenia Gravis, Autoimmune Experimental
Term UI
T366672
Date10/12/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Autoimmune Experimental Myasthenia Gravis
Term UI
T373522
Date10/12/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Experimental Myasthenia
Term UI
T373524
Date10/12/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Experimental Myasthenia Gravis
Term UI
T373525
Date10/12/1999
LexicalTag
NON
ThesaurusID
NLM (2000)