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Neuritis, Autoimmune, Experimental MeSH Descriptor Data 2022


MeSH Heading
Neuritis, Autoimmune, Experimental
Tree Number(s)
C10.114.703.700
C10.668.829.650.500
C20.111.258.625.700
E05.598.500.500.875
Unique ID
D009444
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009444
Annotation
coordinate with GUILLAINE-BARRE SYNDROME if pertinent
Scope Note
An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
Entry Version
NEURITIS AUTOIMMUNE EXPER
Entry Term(s)
Allergic Neuritis, Experimental
Autoimmune Neuritis, Experimental
EAN (Experimental Allergic Neuritis)
EAN (Experimental Autoimmune Neuritis)
Experimental Allergic Neuritis
Experimental Autoimmune Neuritis
Experimental Autoimmune Neuropathy
Neuritis, Experimental Allergic
Neuritis, Experimental Autoimmune
NLM Classification #
WL 544
Previous Indexing
Myelin Sheath (1966-1981)
Neuritis (1966-1981)
Peripheral Nerves (1966-1981)
Public MeSH Note
2005; see NEURITIS, EXPERIMENTAL ALLERGIC 1982-2004
History Note
2005 (1982)
Date Established
1982/01/01
Date of Entry
1981/02/23
Revision Date
2019/07/05
Neuritis, Autoimmune, Experimental Preferred
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