MeSH Browser

MeSH Heading: Exostoses, Multiple Hereditary
Tree Number(s): C04.557.450.565.575.610.615.325; C04.700.330; C05.116.099.708.670.615.325; C05.116.540.310.500; C16.320.700.330
Unique ID: D005097
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005097
Scope Note: Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
Entry Term(s): Bessel-Hagen Disease; Chondrodysplasia, Hereditary Deforming; Diaphyseal Aclasis; Exostoses, Familial; Exostoses, Hereditary Multiple; Exostoses, Multiple; Exostoses, Multiple Cartilaginous; Exostoses, Multiple, Type I; Exostosis, Familial; Exostosis, Hereditary Multiple; Exostosis, Multiple; Exostosis, Multiple Cartilaginous; Familial Exostoses; Hereditary Multiple Exostoses; Hereditary Multiple Exostosis; Multiple Cartilaginous Exostoses; Multiple Hereditary Exostoses; Multiple Osteochondromas; Multiple Osteochondromatosis; Osteochondromas, Multiple
NLM Classification #: WE 250
Previous Indexing: Exostoses (1966-1967)
Public MeSH Note: 90; was EXOSTOSES, MULTIPLE 1968-89
Online Note: use EXOSTOSES, MULTIPLE HEREDITARY to search EXOSTOSES, MULTIPLE 1968-89
History Note: 90; was EXOSTOSES, MULTIPLE 1968-89
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
  - Neoplasms, Connective and Soft Tissue [C04.557.450]
    - Neoplasms, Connective Tissue [C04.557.450.565]
      - Neoplasms, Bone Tissue [C04.557.450.565.575]
        
        Osteochondroma [C04.557.450.565.575.610]
        
        Osteochondromatosis [C04.557.450.565.575.610.615]
        
        Exostoses, Multiple Hereditary [C04.557.450.565.575.610.615.325]

Neoplasms [C04]
- Neoplastic Syndromes, Hereditary [C04.700]

Musculoskeletal Diseases [C05]
- Bone Diseases [C05.116]
  - Bone Diseases, Developmental [C05.116.099]
    - Osteochondrodysplasias [C05.116.099.708]
      - Osteochondroma [C05.116.099.708.670]
        
        Osteochondromatosis [C05.116.099.708.670.615]
        
        Exostoses, Multiple Hereditary [C05.116.099.708.670.615.325]

Musculoskeletal Diseases [C05]
- Bone Diseases [C05.116]
  - Hyperostosis [C05.116.540]
    - Exostoses [C05.116.540.310]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Neoplastic Syndromes, Hereditary [C16.320.700]

Exostoses, Multiple Hereditary Preferred

Concept UI: M0008037
Scope Note: Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
Terms: Exostoses, Multiple Hereditary Preferred Term
Term UI T015605
Date01/01/1999
LexicalTag NON
ThesaurusID; Chondrodysplasia, Hereditary Deforming
Term UI T015598
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Diaphyseal Aclasis
Term UI T015611
Date03/30/1974
LexicalTag NON
ThesaurusID; Exostoses, Familial
Term UI T015600
Date03/20/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostoses, Hereditary Multiple
Term UI T015603
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostoses, Multiple
Term UI T015610
Date03/21/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostoses, Multiple Cartilaginous
Term UI T015608
Date03/20/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostoses, Multiple, Type I
Term UI T811521
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Exostosis, Familial
Term UI T015599
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostosis, Hereditary Multiple
Term UI T015601
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostosis, Multiple
Term UI T015609
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Exostosis, Multiple Cartilaginous
Term UI T015607
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Familial Exostoses
Term UI T841617
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Hereditary Multiple Exostoses
Term UI T015604
Date03/20/1989
LexicalTag NON
ThesaurusID; Hereditary Multiple Exostosis
Term UI T015602
Date05/01/1989
LexicalTag NON
ThesaurusID NLM (1990); Multiple Cartilaginous Exostoses
Term UI T811524
Date11/15/2011
LexicalTag NON
ThesaurusID; Multiple Hereditary Exostoses
Term UI T841618
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Multiple Osteochondromas
Term UI T811525
Date11/15/2011
LexicalTag NON
ThesaurusID; Multiple Osteochondromatosis
Term UI T841619
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Osteochondromas, Multiple
Term UI T015606
Date05/11/1989
LexicalTag NON
ThesaurusID NLM (1990); Bessel-Hagen Disease
Term UI T841616
Date04/18/2013
LexicalTag EPO
ThesaurusID GHR (2014)

Exostoses, Multiple Hereditary MeSH Descriptor Data 2024