MeSH Browser

MeSH Heading: Hamartoma Syndrome, Multiple
Tree Number(s): C04.445.435; C04.651.435; C04.700.435; C16.320.700.435
Unique ID: D006223
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006223
Scope Note: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
Entry Term(s): Bannayan-Riley-Ruvalcaba Syndrome; Bannayan-Ruvalcaba-Riley Syndrome; Bannayan-Zonana Syndrome; Cowden Disease; Cowden Syndrome; Cowden's Disease; Cowden's Syndrome; Dysplastic Gangliocytoma of Cerebellum; Dysplastic Gangliocytoma of the Cerebellum; Lhermitte-Duclos Disease; Macrocephaly, Multiple Lipomas, and Hemangiomata; Macrocephaly, Pseudopapilledema, and Multiple Hemangiomas; Macrocephaly, Pseudopapilledema, and Multiple Hemangiomata; Multiple Hamartoma Syndrome; Myhre-Riley-Smith Syndrome; PTEN Hamartoma Tumor Syndrome; Riley-Smith Syndrome; Ruvalcaba-Myhre Syndrome; Ruvalcaba-Myhre-Smith Syndrome
Previous Indexing: Hamartoma (1966-1986); Neoplasms, Multiple Primary (1966-1986)
Public MeSH Note: 91; was see under NEOPLASMS, MULTIPLE PRIMARY 1987-90
History Note: 91(87); was see under NEOPLASMS, MULTIPLE PRIMARY 1987-90
Date Established: 1991/01/01
Date of Entry: 1986/06/23
Revision Date: 2018/06/29

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Neoplasms [C04]
- Hamartoma [C04.445]

Neoplasms [C04]
- Neoplasms, Multiple Primary [C04.651]

Neoplasms [C04]
- Neoplastic Syndromes, Hereditary [C04.700]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Neoplastic Syndromes, Hereditary [C16.320.700]

Hamartoma Syndrome, Multiple Preferred

Concept UI: M0009775
Scope Note: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
Terms: Hamartoma Syndrome, Multiple Preferred Term
Term UI T018878
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1987); Cowden Disease
Term UI T018875
Date06/23/1986
LexicalTag EPO
ThesaurusID; Cowden Syndrome
Term UI T681637
Date09/19/2006
LexicalTag EPO
ThesaurusID; Cowden's Disease
Term UI T018876
Date06/23/1986
LexicalTag EPO
ThesaurusID; Cowden's Syndrome
Term UI T769474
Date04/15/2010
LexicalTag EPO
ThesaurusID; Multiple Hamartoma Syndrome
Term UI T018877
Date06/23/1986
LexicalTag NON
ThesaurusID

PTEN Hamartoma Tumor Syndrome Related

Lhermitte-Duclos Disease Related

Bannayan-Riley-Ruvalcaba Syndrome Related

Hamartoma Syndrome, Multiple MeSH Descriptor Data 2024