MeSH Browser

MeSH Heading: Hyperlipoproteinemia Type II
Tree Number(s): C16.320.565.398.481; C18.452.584.500.500.644.475; C18.452.584.563.481; C18.452.648.398.481
Unique ID: D006938
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006938
Scope Note: A group of familial disorders characterized by elevated circulating cholesterol contained in either LOW-DENSITY LIPOPROTEINS alone or also in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins).
Entry Term(s): Apolipoprotein B-100, Familial Defective; Apolipoprotein B-100, Familial Ligand-Defective; Familial Combined Hyperlipoproteinemia; Hyper-Low Density Lipoproteinemia; Hyper-Low-Density-Lipoproteinemia; Hyper-beta-Lipoproteinemia; Hyperbetalipoproteinemia; Hypercholesterolemia, Autosomal Dominant; Hypercholesterolemia, Autosomal Dominant, Type B; Hypercholesterolemia, Essential; Hypercholesterolemia, Familial; Hypercholesterolemic Xanthomatosis, Familial; Hyperlipoproteinemia Type 2; Hyperlipoproteinemia Type IIa; Hyperlipoproteinemia Type IIb; Hyperlipoproteinemia, Type II; Hyperlipoproteinemia, Type IIa; LDL Receptor Disorder
Previous Indexing: Hypercholesterolemia (1966-1979); Hyperlipidemia/familial & genetic (1966-1979)
Public MeSH Note: 2007; see HYPERCHOLESTEROLEMIA, FAMILIAL 1980-2007
History Note: 2007 (1980)
Date Established: 1980/01/01
Date of Entry: 1979/04/23
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0486997
Scope Note: Hypercholesterolemia that is caused by mutation in the LOW DENSITY LIPOPROTEIN RECEPTOR gene. This receptor defect prevents LDL binding to the cell membrane and uptake of cholesterol which normally suppresses further cholesterol synthesis.
Terms: Hyperlipoproteinemia Type IIa Preferred Term
Term UI T645972
Date07/15/2005
LexicalTag NON
ThesaurusID NLM (2007); LDL Receptor Disorder
Term UI T645973
Date07/15/2005
LexicalTag NON
ThesaurusID; Hypercholesterolemia, Autosomal Dominant
Term UI T645974
Date07/15/2005
LexicalTag NON
ThesaurusID; Hyperlipoproteinemia, Type IIa
Term UI T824593
Date06/22/2012
LexicalTag NON
ThesaurusID OMIM (2013)

Hyperlipoproteinemia Type II MeSH Descriptor Data 2024