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Job Syndrome MeSH Descriptor Data 2025


MeSH Heading
Job Syndrome
Tree Number(s)
C15.378.553.774.600
C16.320.798.688
C20.673.774.600
C20.673.795.688
Unique ID
D007589
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007589
Scope Note
Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.
Entry Term(s)
Buckley Syndrome
HIE Syndrome
HIES, Autosomal Dominant
HIES, Autosomal Recessive
Hyper-IgE Recurrent Infection Syndrome, Autosomal Recessive
Hyper-IgE Syndrome
Hyper-IgE Syndrome, Autosomal Dominant
Hyper-IgE Syndrome, Autosomal Recessive
Hyper-Immunoglobulin E Syndrome, Autosomal Dominant
Hyper-Immunoglobulin E Syndrome, Autosomal Recessive
Hyperimmunoglobulin E, Recurrent Infection Syndrome
Hyperimmunoglobulin E-Recurrent Infection Syndrome
Hyperimmunoglobulinemia E Syndrome
Job's Syndrome
Job-Buckley Syndrome
Public MeSH Note
2014; see JOB'S SYNDROME 1991-2013; see PHAGOCYTE BACTERICIDAL DYSFUNCTION 1975-1990
History Note
2014 (1975);use PHAGOCYTE BACTERICIDAL DYSFUNCTION 1975-1990
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2019/07/01
Job Syndrome Preferred
Hyper-Immunoglobulin E Syndrome, Autosomal Dominant Narrower
Hyper-Immunoglobulin E Syndrome, Autosomal Recessive Narrower
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