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Bulbar Palsy, Progressive MeSH Descriptor Data 2022


MeSH Heading
Bulbar Palsy, Progressive
Tree Number(s)
C10.574.562.300
C10.668.467.300
Unique ID
D010244
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010244
Scope Note
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)
Entry Term(s)
Bulbar Palsy
Bulbar Palsy, Progressive, Of Childhood
Childhood Progressive Bulbar Palsy
Fazio-Londe Disease
Fazio-Londe Syndrome
Paralysis, Bulbar
Progressive Bulbar Palsy of Childhood
NLM Classification #
WL 310
Public MeSH Note
2000; see PARALYSIS, BULBAR 1966-1999
History Note
2000(1966)
Date Established
2000/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/08
Bulbar Palsy, Progressive Preferred
Bulbar Palsy Broader
Childhood Progressive Bulbar Palsy Narrower
Fazio-Londe Syndrome Narrower
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