MeSH Browser

MeSH Heading: Pyruvate Dehydrogenase (Lipoamide)-Phosphatase
Tree Number(s): D08.811.277.352.650.625.725; D12.776.476.559.725
Unique ID: D011769
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011769
Scope Note: (Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43.
Entry Term(s): PDH Phosphatase; Pyruvate Dehydrogenase Phosphatase; Pyruvate Dehydrogenase Phosphate Phosphatase
Previous Indexing: Ketone Oxidoreductases (1973-1974); Phosphatases (1972-1974); Pyruvates (1973-1974)
Public MeSH Note: 94; was PYRUVATE DEHYDROGENASE PHOSPHATASE 1975-93 (see under PHOSPHOPROTEIN PHOSPHATASES 1979-90, see under PHOSPHOMONOESTERASES 1975-78)
Online Note: use PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE to search PYRUVATE DEHYDROGENASE PHOSPHATASE 1975-93
History Note: 94; was PYRUVATE DEHYDROGENASE PHOSPHATASE 1975-93 (see under PHOSPHOPROTEIN PHOSPHATASES 1979-90, see under PHOSPHOMONOESTERASES 1975-78)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0018292
Scope Note: (Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43.
Terms: Pyruvate Dehydrogenase (Lipoamide)-Phosphatase Preferred Term
Term UI T034787
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); PDH Phosphatase
Term UI T034788
Date12/30/1992
LexicalTag NON
ThesaurusID NLM (1994); Pyruvate Dehydrogenase Phosphatase
Term UI T034785
Date10/08/1992
LexicalTag NON
ThesaurusID NLM (1994); Pyruvate Dehydrogenase Phosphate Phosphatase
Term UI T034786
Date06/29/1983
LexicalTag NON
ThesaurusID UNK (19XX)

Pyruvate Dehydrogenase (Lipoamide)-Phosphatase MeSH Descriptor Data 2024