Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Thioredoxin-Disulfide Reductase MeSH Descriptor Data 2025


MeSH Heading
Thioredoxin-Disulfide Reductase
Tree Number(s)
D08.811.682.667.750
D12.776.331.971
Unique ID
D013880
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013880
Scope Note
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
Entry Term(s)
NADP-Thioredoxin Reductase
NADPH-Thioredoxin Reductase
Thioredoxin Reductase
Thioredoxin Reductase (NADPH)
Registry Numbers
EC 1.8.1.9
Previous Indexing
Bacterial Proteins (1972-1974)
NADH, NADPH Oxidoreductases (1974)
Oxidoreductases (1972-1974)
Public MeSH Note
2008; see THIOREDOXIN REDUCTASE (NADPH) 1991-2007, see NADH, NADPH OXIDOREDUCTASES 1975-1990
History Note
2008(1975)
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2007/07/11
Thioredoxin-Disulfide Reductase Preferred
page delivered in 0.134s