MeSH Browser

MeSH Heading: Thioredoxin-Disulfide Reductase
Tree Number(s): D08.811.682.667.750; D12.776.331.971
Unique ID: D013880
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013880
Scope Note: A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
Entry Term(s): NADP-Thioredoxin Reductase; NADPH-Thioredoxin Reductase; Thioredoxin Reductase; Thioredoxin Reductase (NADPH)
Registry Numbers: EC 1.8.1.9
Previous Indexing: Bacterial Proteins (1972-1974); NADH, NADPH Oxidoreductases (1974); Oxidoreductases (1972-1974)
Public MeSH Note: 2008; see THIOREDOXIN REDUCTASE (NADPH) 1991-2007, see NADH, NADPH OXIDOREDUCTASES 1975-1990
History Note: 2008(1975)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2007/07/11

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0021375
Registry Numbers: EC 1.8.1.9
Scope Note: A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
Terms: Thioredoxin-Disulfide Reductase Preferred Term
Term UI T632219
Date03/02/2005
LexicalTag NON
ThesaurusID NLM (2006); NADP-Thioredoxin Reductase
Term UI T632220
Date03/02/2005
LexicalTag ABX
ThesaurusID NLM (2006); NADPH-Thioredoxin Reductase
Term UI T632221
Date03/02/2005
LexicalTag ABX
ThesaurusID NLM (2006); Thioredoxin Reductase
Term UI T689262
Date01/12/2007
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin Reductase (NADPH)
Term UI T040726
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1975)

Thioredoxin-Disulfide Reductase MeSH Descriptor Data 2025