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Tosyllysine Chloromethyl Ketone MeSH Descriptor Data 2023


MeSH Heading
Tosyllysine Chloromethyl Ketone
Tree Number(s)
D02.455.426.559.389.832.690
D02.886.590.887.600
D12.125.065.850
Unique ID
D014107
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014107
Scope Note
An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process.
Entry Term(s)
Chlorotosylamidoaminoheptanone
TLCK
Tosyllysyl Chloromethane
Pharm Action
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
Registry Number
2104-86-1
CAS Type 1 Name
Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-
Previous Indexing
Chlorine (1974)
Lysine (1974)
Tosyl Compounds (1974)
Public MeSH Note
91; was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under LYSINE 1975-76
History Note
91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under LYSINE 1975-76
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2000/06/22
Tosyllysine Chloromethyl Ketone Preferred
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