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Tosylphenylalanyl Chloromethyl Ketone MeSH Descriptor Data 2023


MeSH Heading
Tosylphenylalanyl Chloromethyl Ketone
Tree Number(s)
D02.455.426.559.389.832.710
D02.886.590.887.660
D12.125.065.930
Unique ID
D014108
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014108
Scope Note
An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
Entry Term(s)
Chlorophenyltosylamidobutanone
TPCK
Tosylphenylalanyl Chloromethane
Pharm Action
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
Registry Number
402-71-1
CAS Type 1 Name
Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)-
Previous Indexing
Chlorine (1974)
Phenylalanine (1972-1974)
Tosyl Compounds (1973-1974)
Public MeSH Note
91; was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76
History Note
91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2000/06/22
Tosylphenylalanyl Chloromethyl Ketone Preferred
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