MeSH Browser

MeSH Heading: Trimethoprim, Sulfamethoxazole Drug Combination
Tree Number(s): D02.065.884.060.300.500; D02.065.884.725.867.500; D02.092.146.807.867.500; D02.455.426.559.389.085.300.500; D02.886.590.700.090.300.500; D02.886.590.700.725.867.500; D03.383.742.906.500; D26.310.875
Unique ID: D015662
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015662
Scope Note: A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
Entry Term(s): Abactrim; Bactifor; Bactrim; Biseptol; Biseptol-480; Centran; Centrin; Co-Trimoxazole; Cotrimoxazole; Drylin; Eslectin; Eusaprim; Insozalin; Kepinol; Kepinol Forte; Lescot; Metomide; Oriprim; Septra; Septrin; Sulfamethoxazole-Trimethoprim Combination; Sulprim; Sumetrolim; TMP SMX; TMP-SMX; Trimedin; Trimethoprim-Sulfamethoxazole; Trimethoprim-Sulfamethoxazole Combination; Trimethoprimsulfa; Trimezole; Trimosulfa
Pharm Action: Anti-Infective Agents, Urinary
Anti-Bacterial Agents
Antimalarials
CAS Type 1 Name: Benzenesulfonamide, 4-a)mino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl-2,4-pyrimidinediamine
Previous Indexing: Drug Combinations (1971-1989); Sulfamethoxazole (1966-1989); Trimethoprim (1972-1989)
Public MeSH Note: 2016
History Note: 2016 (1990)
Date Established: 1990/01/01
Date of Entry: 1989/09/01
Revision Date: 2023/06/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Amides [D02.065]
  - Sulfonamides [D02.065.884]
    - Benzenesulfonamides [D02.065.884.060]
      - Sulfamethoxazole [D02.065.884.060.300]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.065.884.060.300.500]

Organic Chemicals [D02]
- Amides [D02.065]
  - Sulfonamides [D02.065.884]
    - Sulfanilamides [D02.065.884.725]
      - Sulfamethoxazole [D02.065.884.725.867]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.065.884.725.867.500]

Organic Chemicals [D02]
- Amines [D02.092]
  - Aniline Compounds [D02.092.146]
    - Sulfanilamides [D02.092.146.807]
      - Sulfamethoxazole [D02.092.146.807.867]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.092.146.807.867.500]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Benzenesulfonamides [D02.455.426.559.389.085]
        
        Sulfamethoxazole [D02.455.426.559.389.085.300]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.455.426.559.389.085.300.500]

Organic Chemicals [D02]
- Sulfur Compounds [D02.886]
  - Sulfones [D02.886.590]
    - Sulfonamides [D02.886.590.700]
      - Benzenesulfonamides [D02.886.590.700.090]
        
        Sulfamethoxazole [D02.886.590.700.090.300]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.886.590.700.090.300.500]

Organic Chemicals [D02]
- Sulfur Compounds [D02.886]
  - Sulfones [D02.886.590]
    - Sulfonamides [D02.886.590.700]
      - Sulfanilamides [D02.886.590.700.725]
        
        Sulfamethoxazole [D02.886.590.700.725.867]
        
        Trimethoprim, Sulfamethoxazole Drug Combination [D02.886.590.700.725.867.500]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, 1-Ring [D03.383]
  - Pyrimidines [D03.383.742]
    - Trimethoprim [D03.383.742.906]
      - Trimethoprim, Sulfamethoxazole Drug Combination [D03.383.742.906.500]

Pharmaceutical Preparations [D26]
- Drug Combinations [D26.310]

Trimethoprim, Sulfamethoxazole Drug Combination Preferred

Concept UI: M0024001
Scope Note: A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
Terms: Trimethoprim, Sulfamethoxazole Drug Combination Preferred Term
Term UI T000881383
Date06/05/2015
LexicalTag NON
ThesaurusID NLM (2016); Centran
Term UI T046341
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Centrin
Term UI T046342
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Cotrimoxazole
Term UI T046343
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Eslectin
Term UI T046344
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Insozalin
Term UI T046345
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Trimedin
Term UI T046346
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Trimethoprim-Sulfamethoxazole
Term UI T046347
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Sulfamethoxazole-Trimethoprim Combination
Term UI T046348
Date04/11/1997
LexicalTag NON
ThesaurusID NLM (1998); Trimethoprim-Sulfamethoxazole Combination
Term UI T046349
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Trimezole
Term UI T046350
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); Co-Trimoxazole
Term UI T046351
Date02/03/1989
LexicalTag NON
ThesaurusID NLM (1990); TMP SMX
Term UI T046352
Date04/11/1997
LexicalTag ABB
ThesaurusID NLM (1998); TMP-SMX
Term UI T046353
Date04/11/1997
LexicalTag ABB
ThesaurusID NLM (1998)