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Cilastatin, Imipenem Drug Combination MeSH Descriptor Data 2025
Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.
2019; CILASTATIN, IMIPENEM DRUG COMBINATION was indexed under CILASTATIN and IMIPENEM 1995-2018 and 1988-1994; under DRUG COMBINATIONS 1995-2018 and 1985-1994; and under CYCLOPROPANES and THIENAMYCINS 1985-1988
Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.