MeSH Browser

MeSH Heading: Guanine Nucleotide-Releasing Factor 2
Tree Number(s): D12.644.360.325.300.300; D12.776.476.325.300.300
Unique ID: D020735
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020735
Scope Note: A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
Entry Term(s): C3G Protein; GRF-2; GRF2; GRF2 Protein; GRF2 Protein, Mammalian; Guanine Nucleotide Exchange Factor C3G; RAP1GRF1
Previous Indexing: Proteins (1997-1999)
Public MeSH Note: 2000; GRF2 PROTEIN, MAMMALIAN was indexed under PROTEINS 1995-1999; C3G PROTEIN was indexed under PROTEINS 1997-1999
History Note: 2000; use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1997-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0328202
Scope Note: A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
Terms: Guanine Nucleotide-Releasing Factor 2 Preferred Term
Term UI T358202
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); GRF2 Protein, Mammalian
Term UI T095420
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Guanine Nucleotide Exchange Factor C3G
Term UI T362188
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); GRF2
Term UI T362189
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); GRF2 Protein
Term UI T362190
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); GRF-2
Term UI T362191
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); C3G Protein
Term UI T095412
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); RAP1GRF1
Term UI T362192
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Guanine Nucleotide-Releasing Factor 2 MeSH Descriptor Data 2024