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Rho Guanine Nucleotide Exchange Factors MeSH Descriptor Data 2025


MeSH Heading
Rho Guanine Nucleotide Exchange Factors
Tree Number(s)
D12.644.360.325.300.099
D12.776.476.325.300.099
Unique ID
D064067
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D064067
Scope Note
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
Entry Term(s)
ARHGEF1
Cool-1 Protein
PAK-Interacting Exchange Factor beta
Rho Guanine Nucleotide Exchange Factor (GEF) 1
Rho Guanine Nucleotide Exchange Factor 6
Rho Guanine Nucleotide Exchange Factor 7
Rho Guanine Nucleotide Exchange Factor p115
RhoGEF
beta PIX Protein
betaPIX Protein
p115 RhoGEF
p115RhoGEF
Registry Numbers
0
Public MeSH Note
2014; was indexed under GUANINE NUCLEOTIDE EXCHANGE FACTORS
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/08
Revision Date
2015/11/24
Rho Guanine Nucleotide Exchange Factors Preferred
Rho Guanine Nucleotide Exchange Factor p115 Narrower
Rho Guanine Nucleotide Exchange Factor 7 Narrower
Rho Guanine Nucleotide Exchange Factor 6 Narrower
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