MeSH Browser

MeSH Heading: Penicillin-Binding Proteins
Tree Number(s): D08.811.710; D12.776.097.545
Unique ID: D046915
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D046915
Scope Note: Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.
Entry Term(s): Penicillin-Binding Protein; Penicillin-Binding Protein 1; Penicillin-Binding Protein 1A; Penicillin-Binding Protein 1b; Penicillin-Binding Protein 2; Penicillin-Binding Protein 2a; Penicillin-Binding Protein 2b; Penicillin-Binding Protein 3; Penicillin-Binding Protein 4; Penicillin-Binding Protein 5; Penicillin-Binding Protein 6; Penicillin-Binding Protein 7; Penicillin-Binding Protein-2a; Peptidoglycan Synthetase
Registry Numbers: 0; 9042-06-2
Related Numbers: 9042-06-2; EC 2.4.1.129
Previous Indexing: Bacterial Proteins (1978-2004); Carrier Proteins (1978-2004); Hexosyltransferases (1999-2004); Muramoylpentapeptide Carboxypeptidase (1978-2004); Peptidyltransferase (1978-2004)
See Also: Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Peptidyl Transferases
Public MeSH Note: 2005; PENICILLIN-BINDING PROTEINS was indexed under HEXOSYLTRANSFERASES 1999-2004, under BACTERIAL PROTEINS, MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; CARRIER PROTEINS, & PEPTIDYLTRANSFERASE 1978-2004
History Note: 2005 (1978);
Date Established: 2005/01/01
Date of Entry: 2004/07/08
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Bacterial Proteins [D12.776.097]

Penicillin-Binding Proteins Preferred

Penicillin-Binding Protein 1 Narrower

Penicillin-Binding Protein 5 Narrower

Penicillin-Binding Protein 7 Narrower

Penicillin-Binding Protein 2a Narrower

Penicillin-Binding Protein 4 Narrower

Penicillin-Binding Protein 1A Narrower

Penicillin-Binding Protein 1b Narrower

Penicillin-Binding Protein 2 Narrower

Penicillin-Binding Protein 3 Narrower

Peptidoglycan Synthetase Related

Penicillin-Binding Protein 6 Narrower

Penicillin-Binding Protein 2b Narrower

Penicillin-Binding Proteins MeSH Descriptor Data 2025