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Penicillin-Binding Proteins
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Penicillin-Binding Proteins
Tree Number(s)
D08.811.710
D12.776.097.545
Unique ID
D046915
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D046915
Scope Note
Bacterial proteins that share the property of binding irreversibly to
PENICILLINS
and other
ANTIBACTERIAL AGENTS
derived from
LACTAMS
. The penicillin-binding proteins are primarily enzymes involved in
CELL WALL
biosynthesis including
MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE
;
PEPTIDE SYNTHASES
;
TRANSPEPTIDASES
; and
HEXOSYLTRANSFERASES
.
Entry Term(s)
Penicillin-Binding Protein
Penicillin-Binding Protein 1
Penicillin-Binding Protein 1A
Penicillin-Binding Protein 1b
Penicillin-Binding Protein 2
Penicillin-Binding Protein 2a
Penicillin-Binding Protein 2b
Penicillin-Binding Protein 3
Penicillin-Binding Protein 4
Penicillin-Binding Protein 5
Penicillin-Binding Protein 6
Penicillin-Binding Protein 7
Penicillin-Binding Protein-2a
Peptidoglycan Synthetase
Registry Number
0
Related Numbers
9042-06-2
EC 2.4.1.129
Previous Indexing
Bacterial Proteins (1978-2004)
Carrier Proteins (1978-2004)
Hexosyltransferases (1999-2004)
Muramoylpentapeptide Carboxypeptidase (1978-2004)
Peptidyltransferase (1978-2004)
See Also
Hexosyltransferases
Muramoylpentapeptide Carboxypeptidase
Peptidyl Transferases
Public MeSH Note
2005; PENICILLIN-BINDING PROTEINS was indexed under HEXOSYLTRANSFERASES 1999-2004, under BACTERIAL PROTEINS, MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; CARRIER PROTEINS, & PEPTIDYLTRANSFERASE 1978-2004
History Note
2005 (1978);
Date Established
2005/01/01
Date of Entry
2004/07/08
Revision Date
2013/07/09
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Deubiquitinating Enzymes [D08.811.037]
DNA Repair Enzymes [D08.811.074]
DNA Restriction-Modification Enzymes [D08.811.150]
DNA, Catalytic [D08.811.165]
Enzymes, Immobilized [D08.811.180]
Holoenzymes [D08.811.255]
Hydrolases [D08.811.277]
Isoenzymes [D08.811.348]
Isomerases [D08.811.399]
Ligases [D08.811.464]
Lyases [D08.811.520]
Multienzyme Complexes [D08.811.600]
Multifunctional Enzymes [D08.811.641]
Oxidoreductases [D08.811.682]
Penicillin-Binding Proteins [D08.811.710]
Recombinases [D08.811.739]
RNA, Catalytic [D08.811.797]
Transferases [D08.811.913]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Bacterial Proteins [D12.776.097]
Antigens, Bacterial [D12.776.097.025]
AraC Transcription Factor [D12.776.097.049]
Azurin [D12.776.097.100]
Bacterial Outer Membrane Proteins [D12.776.097.120]
Bacterial Proton-Translocating ATPases [D12.776.097.130]
Bacteriocins [D12.776.097.151]
Botulinum Toxins [D12.776.097.156]
Cell Wall Skeleton [D12.776.097.162]
Coagulase [D12.776.097.181]
Colicins [D12.776.097.200]
CRISPR-Associated Protein 9 [D12.776.097.219]
DNA Gyrase [D12.776.097.237]
DNA Topoisomerase IV [D12.776.097.256]
Escherichia coli Proteins [D12.776.097.275]
Exfoliatins [D12.776.097.293]
Factor For Inversion Stimulation Protein [D12.776.097.312]
Ferredoxins [D12.776.097.350]
Flagellin [D12.776.097.380]
Flavodoxin [D12.776.097.400]
Integration Host Factors [D12.776.097.513]
Lac Repressors [D12.776.097.521]
Luciferases, Bacterial [D12.776.097.529]
Methyl-Accepting Chemotaxis Proteins [D12.776.097.533]
MutS DNA Mismatch-Binding Protein [D12.776.097.537]
NADP Transhydrogenase, B-Specific [D12.776.097.541]
Penicillin-Binding Proteins [D12.776.097.545]
Periplasmic Proteins [D12.776.097.577]
RNA Polymerase Sigma 54 [D12.776.097.698]
Staphylococcal Protein A [D12.776.097.820]
Streptavidin [D12.776.097.835]
Tetanus Toxin [D12.776.097.872]
Transcription Activator-Like Effectors [D12.776.097.890]
Expand All
Collapse All
Penicillin-Binding Proteins
Preferred
Concept UI
M0068526
Registry Number
0
Related Numbers
9042-06-2
EC 2.4.1.129
Scope Note
Bacterial proteins that share the property of binding irreversibly to
PENICILLINS
and other
ANTIBACTERIAL AGENTS
derived from
LACTAMS
. The penicillin-binding proteins are primarily enzymes involved in
CELL WALL
biosynthesis including
MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE
;
PEPTIDE SYNTHASES
;
TRANSPEPTIDASES
; and
HEXOSYLTRANSFERASES
.
Terms
Penicillin-Binding Proteins
Preferred Term
Term UI
T098528
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein
Term UI
T098529
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 1A
Narrower
Concept UI
M0107496
Registry Number
0
Terms
Penicillin-Binding Protein 1A
Preferred Term
Term UI
T137500
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 1b
Narrower
Concept UI
M0107498
Registry Number
0
Terms
Penicillin-Binding Protein 1b
Preferred Term
Term UI
T137502
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 2
Narrower
Concept UI
M0107499
Registry Number
0
Terms
Penicillin-Binding Protein 2
Preferred Term
Term UI
T137503
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 2a
Narrower
Concept UI
M0068523
Registry Number
0
Terms
Penicillin-Binding Protein 2a
Preferred Term
Term UI
T552250
Date
10/02/2003
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein-2a
Term UI
T098526
LexicalTag
NON
ThesaurusID
NLM (2005)
Peptidoglycan Synthetase
Related
Concept UI
M0107502
Registry Number
9042-06-2
Scope Note
A complex of enzymes that synthesize the peptidoglycan cell wall structure.
Terms
Peptidoglycan Synthetase
Preferred Term
Term UI
T137506
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 3
Narrower
Concept UI
M0107500
Registry Number
0
Terms
Penicillin-Binding Protein 3
Preferred Term
Term UI
T137504
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 4
Narrower
Concept UI
M0068524
Registry Number
0
Terms
Penicillin-Binding Protein 4
Preferred Term
Term UI
T098527
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 5
Narrower
Concept UI
M0068521
Registry Number
0
Terms
Penicillin-Binding Protein 5
Preferred Term
Term UI
T098524
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 6
Narrower
Concept UI
M0068518
Registry Number
0
Terms
Penicillin-Binding Protein 6
Preferred Term
Term UI
T098521
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 7
Narrower
Concept UI
M0068522
Registry Number
0
Terms
Penicillin-Binding Protein 7
Preferred Term
Term UI
T098525
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 1
Narrower
Concept UI
M0068519
Registry Number
0
Terms
Penicillin-Binding Protein 1
Preferred Term
Term UI
T098522
LexicalTag
NON
ThesaurusID
NLM (2005)
Penicillin-Binding Protein 2b
Narrower
Concept UI
M0454417
Registry Number
0
Terms
Penicillin-Binding Protein 2b
Preferred Term
Term UI
T552274
Date
10/02/2003
LexicalTag
NON
ThesaurusID
NLM (2005)
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