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Proteasome Endopeptidase Complex MeSH Descriptor Data 2022


MeSH Heading
Proteasome Endopeptidase Complex
Tree Number(s)
D05.500.562.500
D08.811.277.656.918
D08.811.600.730
Unique ID
D046988
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D046988
Scope Note
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Entry Term(s)
20S Proteasome
Ingensin
Macropain
Macroxyproteinase
Multicatalytic Endopeptidase Complex
Multicatalytic Proteinase
Prosome
Proteasome
Registry Number
EC 3.4.25.1
Related Numbers
EC 3.4.25.1
Previous Indexing
Cysteine Endopeptidases (1986-2004)
Multienzyme Complexes (1986-2004)
See Also
Ubiquitin-Protein Ligase Complexes
Public MeSH Note
2005; PROTEASOME ENDOPEPTIDASE COMPLEX was indexed under CYSTEINE ENDOPEPTIDASES & MULTIENZYME COMPLEXES 1986-2004
History Note
2005; use PROTEASOME ENDOPEPTIDASE COMPLEX (NM) 1986-2004
Entry Combination
antagonists & inhibitors:Proteasome Inhibitors
Date Established
2005/01/01
Date of Entry
2004/07/07
Revision Date
2012/07/03
Proteasome Endopeptidase Complex Preferred
Ingensin Narrower
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