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Polyketide Synthases
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Polyketide Synthases
Tree Number(s)
D08.811.464.257.275
D08.811.600.715
Unique ID
D048630
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D048630
Scope Note
Large enzyme complexes composed of a number of component enzymes that are found in
STREPTOMYCES
which biosynthesize
MACROLIDES
and other polyketides.
Entry Term(s)
6-Deoxyerythronolide-B Synthase
Epothilone Polyketide Synthase
Erythromycin Polyketide Synthase
Griseusin Polyketide Synthase
Niddamycin Polyketide Synthase
Polyketide Synthase
Polyketide Synthase L1
Polyketide Synthase WA
Rifamycin Polyketide Synthase
Sterigmatocystin Polyketide Synthase
Type I Polyketide Synthase
Type II Polyketide Beta-Ketoacyl Synthase
Urdamycin Polyketide Synthase
WdPKS1 Protein
WhiE Polyketide Synthase
Registry Numbers
79956-01-7
0
128172-72-5
Related Numbers
128172-72-5
Previous Indexing
Multienzyme Complexes (1989-2004)
Public MeSH Note
2005; POLYKETIDE SYNTHASE was indexed under MULTIENZYME COMPLEXES 1989-2004
History Note
2005(1989)
Date Established
2005/01/01
Date of Entry
2004/07/08
Revision Date
2020/05/27
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Ligases [D08.811.464]
Carbon-Carbon Ligases [D08.811.464.257]
Acetyl-CoA Carboxylase [D08.811.464.257.050]
Polyketide Synthases [D08.811.464.257.275]
Pyruvate Carboxylase [D08.811.464.257.500]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Multienzyme Complexes [D08.811.600]
Anthranilate Phosphoribosyltransferase [D08.811.600.075]
Anthranilate Synthase [D08.811.600.085]
Electron Transport Chain Complex Proteins [D08.811.600.250]
Exosome Multienzyme Ribonuclease Complex [D08.811.600.283]
Fatty Acid Synthase, Type II [D08.811.600.354]
Glycine Decarboxylase Complex [D08.811.600.391]
Ketoglutarate Dehydrogenase Complex [D08.811.600.465]
Mi-2 Nucleosome Remodeling and Deacetylase Complex [D08.811.600.620]
Phosphoenolpyruvate Sugar Phosphotransferase System [D08.811.600.700]
Photosynthetic Reaction Center Complex Proteins [D08.811.600.710]
Polyketide Synthases [D08.811.600.715]
Prostaglandin-Endoperoxide Synthases [D08.811.600.720]
Proteasome Endopeptidase Complex [D08.811.600.730]
Pyruvate Dehydrogenase Complex [D08.811.600.741]
Sin3 Histone Deacetylase and Corepressor Complex [D08.811.600.795]
Sucrase-Isomaltase Complex [D08.811.600.850]
Tryptophan Synthase [D08.811.600.896]
Viral Replicase Complex Proteins [D08.811.600.948]
Expand All
Collapse All
Polyketide Synthases
Preferred
Concept UI
M0171396
Registry Numbers
79956-01-7
Related Numbers
128172-72-5
Scope Note
Large enzyme complexes composed of a number of component enzymes that are found in
STREPTOMYCES
which biosynthesize
MACROLIDES
and other polyketides.
Terms
Polyketide Synthases
Preferred Term
Term UI
T201401
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Polyketide Synthase
Term UI
T000996366
Date
11/14/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
Griseusin Polyketide Synthase
Narrower
Concept UI
M0171386
Registry Numbers
0
Terms
Griseusin Polyketide Synthase
Preferred Term
Term UI
T201391
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Niddamycin Polyketide Synthase
Narrower
Concept UI
M0171387
Registry Numbers
0
Terms
Niddamycin Polyketide Synthase
Preferred Term
Term UI
T201392
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Polyketide Synthase L1
Narrower
Concept UI
M0171390
Registry Numbers
0
Terms
Polyketide Synthase L1
Preferred Term
Term UI
T201395
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Sterigmatocystin Polyketide Synthase
Narrower
Concept UI
M0171391
Registry Numbers
0
Terms
Sterigmatocystin Polyketide Synthase
Preferred Term
Term UI
T201396
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Type I Polyketide Synthase
Narrower
Concept UI
M0171392
Registry Numbers
0
Terms
Type I Polyketide Synthase
Preferred Term
Term UI
T201397
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Type II Polyketide Beta-Ketoacyl Synthase
Narrower
Concept UI
M0171393
Registry Numbers
0
Terms
Type II Polyketide Beta-Ketoacyl Synthase
Preferred Term
Term UI
T201398
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Urdamycin Polyketide Synthase
Narrower
Concept UI
M0171394
Registry Numbers
0
Terms
Urdamycin Polyketide Synthase
Preferred Term
Term UI
T201399
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
WhiE Polyketide Synthase
Narrower
Concept UI
M0171395
Registry Numbers
0
Terms
WhiE Polyketide Synthase
Preferred Term
Term UI
T576084
Date
03/09/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
6-Deoxyerythronolide-B Synthase
Narrower
Concept UI
M0324448
Registry Numbers
128172-72-5
Terms
6-Deoxyerythronolide-B Synthase
Preferred Term
Term UI
T201386
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Rifamycin Polyketide Synthase
Narrower
Concept UI
M0333181
Registry Numbers
0
Terms
Rifamycin Polyketide Synthase
Preferred Term
Term UI
T364861
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
WdPKS1 Protein
Narrower
Concept UI
M0353930
Registry Numbers
0
Terms
WdPKS1 Protein
Preferred Term
Term UI
T403047
Date
12/17/1999
LexicalTag
NON
ThesaurusID
NLM (2005)
Epothilone Polyketide Synthase
Narrower
Concept UI
M0357204
Registry Numbers
0
Terms
Epothilone Polyketide Synthase
Preferred Term
Term UI
T407313
Date
02/16/2000
LexicalTag
NON
ThesaurusID
NLM (2005)
Erythromycin Polyketide Synthase
Narrower
Concept UI
M0171384
Registry Numbers
0
Terms
Erythromycin Polyketide Synthase
Preferred Term
Term UI
T201389
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2005)
Polyketide Synthase WA
Narrower
Concept UI
M0392968
Registry Numbers
0
Terms
Polyketide Synthase WA
Preferred Term
Term UI
T453760
Date
07/10/2001
LexicalTag
NON
ThesaurusID
NLM (2005)
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