Smad Proteins, Inhibitory MeSH Descriptor Data 2024

MeSH Heading: Smad Proteins, Inhibitory
Tree Number(s): D12.644.360.024.334.200; D12.776.157.057.170.249; D12.776.476.024.428.249
Unique ID: D051897
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051897
Scope Note: A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They form autoinhibitory feedback loops in the TGF-BETA signaling pathway and mediate signaling cross-talk with other signaling pathways
Entry Term(s): I-Smad Proteins; Inhibitory Smad Proteins
Registry Number: 0
Public MeSH Note: 2006
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - Smad Proteins [D12.644.360.024.334]
        
        Smad Proteins, Inhibitory [D12.644.360.024.334.200]
        
        Smad6 Protein [D12.644.360.024.334.200.600]
        
        Smad7 Protein [D12.644.360.024.334.200.700]
        
        Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
        
        Smad4 Protein [D12.644.360.024.334.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Smad Proteins [D12.776.157.057.170]
        
        Smad Proteins, Inhibitory [D12.776.157.057.170.249]
        
        Smad6 Protein [D12.776.157.057.170.249.600]
        
        Smad7 Protein [D12.776.157.057.170.249.700]
        
        Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
        
        Smad4 Protein [D12.776.157.057.170.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Smad Proteins [D12.776.476.024.428]
        
        Smad Proteins, Inhibitory [D12.776.476.024.428.249]
        
        Smad6 Protein [D12.776.476.024.428.249.600]
        
        Smad7 Protein [D12.776.476.024.428.249.700]
        
        Smad Proteins, Receptor-Regulated [D12.776.476.024.428.500]
        
        Smad4 Protein [D12.776.476.024.428.750]

Smad Proteins, Inhibitory Preferred

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