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Nicotinamide Phosphoribosyltransferase MeSH Descriptor Data 2025
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
Entry Term(s)
NAMPT Protein
NAmPRTase
NMN Pyrophosphorylase
Pre-B-Cell Colony-Enhancing Factor
Visfatin
Registry Numbers
EC 2.4.2.12
Related Numbers
9030-27-7
Previous Indexing
Pentosyltransferases (1972-2007)
Public MeSH Note
2008; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE was indexed under PENTOSYLTRANSFERASES 1982-2007
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).