MeSH Browser

MeSH Heading: Nicotinamide Phosphoribosyltransferase
Tree Number(s): D08.811.913.400.725.575
Unique ID: D054409
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054409
Scope Note: An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
Entry Term(s): NAMPT Protein; NAmPRTase; NMN Pyrophosphorylase; Pre-B-Cell Colony-Enhancing Factor; Visfatin
Related Numbers: 9030-27-7
Previous Indexing: Pentosyltransferases (1972-2007)
Public MeSH Note: 2008; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE was indexed under PENTOSYLTRANSFERASES 1982-2007
History Note: 2008 (1982)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0103184
Related Numbers: 9030-27-7
Scope Note: An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
Terms: Nicotinamide Phosphoribosyltransferase Preferred Term
Term UI T133188
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); NAmPRTase
Term UI T687670
Date12/12/2006
LexicalTag ACX
ThesaurusID NLM (2008); NAMPT Protein
Term UI T687669
Date12/12/2006
LexicalTag ACX
ThesaurusID NLM (2008); NMN Pyrophosphorylase
Term UI T133187
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2008); Pre-B-Cell Colony-Enhancing Factor
Term UI T687672
Date12/12/2006
LexicalTag NON
ThesaurusID NLM (2008); Visfatin
Term UI T687671
Date12/12/2006
LexicalTag NON
ThesaurusID NLM (2008)

Nicotinamide Phosphoribosyltransferase MeSH Descriptor Data 2024